The science behind Lectranal®

Human studies

Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis

Matkovic Z, Zivkovic V, Korica M, Plavec D, Pecanic S, Tudoric N. Phytother Res. 2010. 24(2): 175-181.

Study design: Double-blind, placebo-controlled clinical trial

Treatment: 48 patients with moderate to severe seasonal allergic rhinitis (SAR) who are allergic to specific pollens were divided randomly into 2 groups receiving either Lectranal® or a placebo (2 capsules, twice daily) for 6 weeks.

Lectranal® is efficient and safe in the treatment of allergic rhinitis and has significantly better results for several outcomes than the placebo.


Animal studies

Lectranal® regulates the expression of 21 different genes involved in the inflammatory process

Hadžija M., Hadžija Popović M., Korolija M., Lectranal®, INFLAMMATORY REACTION AND GENE EXPRESSION IN MOUSE SPLEEN, Ruđer Bošković Institute, Zagreb 2005

Lectranal® is a powerful immunoregulator

Hadžija M., Popović Hadžija M., Korolija M., Križanac S., THE EFFECT OF Lectranal® ON THE IMMUNOREGULATION OF INFLAMMATORY PROCESSES IN MICE (ikbkg, relb, and cd3e gene activity, using RT-PCR technology), Ruđer Bošković Institute, Zagreb 2006

Lectranal® treatment significantly increases the IgG concentration

Hadžija M., Popović Hadžija M., Korolija M., AN ASSAY FOR IMMUNOGLOBULINES IN THE BLOOD OF MICE TREATED WITH Lectranal®, Ruđer Bošković Institute, Zagreb 2006

Lectranal® reduces skin edema

Hadžija M., Popović Hadžija M., Korolija M., Lectranal® AND INTRADERMAL INFLAMMATORY REACTIONS, Ruđer Bošković Institute, Zagreb 2006


Safety

Astragalus - Classified as "herb that can safely be consumed when used appropriately"

American Herbal Products Association

Lectranal® - No toxicity effects of any kind + good safety record

Hadžija M., Popović Hadžija M., Korolija M., Križanac S., Lectranal® - PRECLINICAL TOXICOLOGICAL STUDY, Ruđer Bošković Institute, Zagreb 2007