Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis
Matkovic Z, Zivkovic V, Korica M, Plavec D, Pecanic S, Tudoric N. Phytother Res. 2010. 24(2): 175-181.
Study design: Double-blind, placebo-controlled clinical trial
Treatment: 48 patients with moderate to severe seasonal allergic rhinitis (SAR) who are allergic to specific pollens were divided randomly into 2 groups receiving either Lectranal® or a placebo (2 capsules, twice daily) for 6 weeks.
Lectranal® regulates the expression of 21 different genes involved in the inflammatory process
Hadžija M., Hadžija Popović M., Korolija M., Lectranal®, INFLAMMATORY REACTION AND GENE EXPRESSION IN MOUSE SPLEEN, Ruđer Bošković Institute, Zagreb 2005
Lectranal® is a powerful immunoregulator
Hadžija M., Popović Hadžija M., Korolija M., Križanac S., THE EFFECT OF Lectranal® ON THE IMMUNOREGULATION OF INFLAMMATORY PROCESSES IN MICE (ikbkg, relb, and cd3e gene activity, using RT-PCR technology), Ruđer Bošković Institute, Zagreb 2006
Lectranal® treatment significantly increases the IgG concentration
Hadžija M., Popović Hadžija M., Korolija M., AN ASSAY FOR IMMUNOGLOBULINES IN THE BLOOD OF MICE TREATED WITH Lectranal®, Ruđer Bošković Institute, Zagreb 2006
Lectranal® reduces skin edema
Hadžija M., Popović Hadžija M., Korolija M., Lectranal® AND INTRADERMAL INFLAMMATORY REACTIONS, Ruđer Bošković Institute, Zagreb 2006
Astragalus - Classified as "herb that can safely be consumed when used appropriately"
American Herbal Products Association
Lectranal® - No toxicity effects of any kind + good safety record
Hadžija M., Popović Hadžija M., Korolija M., Križanac S., Lectranal® - PRECLINICAL TOXICOLOGICAL STUDY, Ruđer Bošković Institute, Zagreb 2007
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